02/12/2008
Mobility
Mobility has been a major concern in my household for quite some time. Thanks to her spinal surgeries and her recent fall, my wife has had to rely on walkers and/or a cane. After prolonged periods of lying around it’s of utmost importance to work on restoring mobility and resuming a walking program, which I hope we can accomplish this week. Mobility is a theme of three articles I’ve come across recently.
An AP article in the Star-Ledger dealt with the work of researchers from the Max Planck Institute of Evolutionary Anthropology on a 40,000-year-old tooth found in the only Neandertal remains ever discovered in Greece. By analyzing the tooth for the element strontium the team showed that the person to whom the tooth belonged died at least 12.5 miles from the place where he or she grew up. Katerina Harvati of the Max Planck group is quoted to the effect that this is a surprising finding showing that the Neandertals were a more mobile group than had been previously thought.
If I recall correctly, we’ve discussed in a past column a similar study on the famed Ice Man who died a few thousand years ago and was recently found in a glacier in remarkably well preserved condition. As teeth grow they incorporate amounts of certain elements found in the water and surrounding environment. Strontium is in the same family of elements as calcium and should be incorporated in bones and teeth. By analyzing the Neandertal tooth for strontium in the layers of the tooth, and presumably armed with a knowledge of the variation in strontium in the region surrounding the site where the tooth was found, the mobility of the person was traced.
One fellow, Neandertal expert Clive Finlayson, not impressed with the fuss over a Neandertal traveling 12 miles from a given site, is quoted as saying, “We’re talking about humans, not trees.” I must admit that, having walked three or four miles from my starting point when we went to Marco Island, I would be amazed if the Neandertals, a hunting bunch, wouldn’t move around more than that in search of prime hunting areas after taking out the game from one location.
Can mobility help out with the energy problem? You may have seen the news article on the work of Max Donelan of the University of Pittsburgh and colleagues from the University of Michigan. They have developed a device that generates electricity from the swing of the knee during walking. Sunday’s Star-Ledger has a brief article and picture of a walker wearing the device. The device in the picture rides above the knee and is attached to a wrap around the knee. The device relies on a principle similar to the recharging of a hybrid vehicle battery on braking. As the knee decelerates, the device generates the electricity. Reportedly, walking for only a minute will generate enough electricity to power a cell phone for ten minutes.
Does this mean that in the future every cell phone will come with a cord and plug-in for attaching to this device above the knee? On a recent outing, I swear half the people walking were talking on their cell phones. The article didn’t mention a probable cost of such a device but if it eliminates the need for plugging in to a charger, it may have a real future.
This week a space shuttle installed a new science lab on the International Space Station. A big problem for astronauts spending extended periods of time in the zero gravity of space is atrophy of muscles. On truly long periods in space this could be a major mobility problem. It would be a disaster if our Mars mission ever transpired and the astronauts couldn’t walk when they got there. An article by Bo Schwerin in the Fall 2007 issue of the Pitt Magazine concerns another study going on at the University of Pittsburgh that relates to this mobility problem.
Beth Oczypok is only a sophomore at Pitt but she and her mentor, Nate Szewczyk (I’ll leave it to the reader to pronounce these names correctly), are directly involved with thousands of astronauts who spent six months on the International Space Station! OK, these were not human astronauts. They were worms known in the trade as C. elegans, a worm we’ve discussed a number of times in these columns and certainly one of the most studied organisms in science. The object of the study was to study the atrophy of muscles in space and the six months spent by the worms up there were “the equivalent of 28 generations in worm years.” Plenty of time for any muscle problems to show up – and they did.
Fortunately, we humans share many comparable genes with C. elegans and some of them are related to muscles. Sure enough, as do he human astronauts, the worms function fine in space. However, on return to Earth they do have some sort of movement defect, just as with the human space travelers. The Pitt article says that the researchers have found a muscle protein attachment complex that experimentally and after space flightis decreased in the worms and the decrease results in atrophy. The hope is that perhaps Beth will find a way to block the decrease in the protein and that, if so, it will help address the atrophy problem in humans.
This is certainly quite an impressive accomplishment for a college sophomore and our Beth has certainly had an unusual experience with the worms in space. All space travelers deserve an appropriate greeting upon their return to terra firma. Accordingly, Beth was on hand in Florida to retrieve the critters when the shuttle Atlantis landed. The only problem was that due to weather conditions the shuttle had to land at Edwards Air Force base in California! It was an overnight flight to California and the exhausted sophomore had the worms safely tucked away in the appropriate container a few hours after touchdown.
Well, as I finish this column, snow is falling and a “wintry mix” is due for tonight. Mobility on icy roads will be a problem in many spots. Stay upright and/or on target.
Allen F. Bortrum
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